Medical Terminology Suffixes (With Meanings and Examples)

A medical suffix attaches to the end of a term and usually indicates a condition, procedure, or diagnosis. Here are the high-frequency suffixes with meanings and clinical examples.

SuffixMeaningExample
-algiapainarthralgia, neuralgia
-ectomysurgical removalappendectomy, cholecystectomy
-emiablood conditionanemia, hyperglycemia
-genesisorigin, productiononcogenesis, hematopoiesis
-gramrecord, imageelectrocardiogram, mammogram
-graphyprocess of recordingechocardiography, angiography
-itisinflammationappendicitis, hepatitis
-logystudy ofcardiology, neurology
-lysisbreakdown, destructionhemolysis, fibrinolysis
-megalyenlargementhepatomegaly, splenomegaly
-omatumor, massmelanoma, carcinoma
-osiscondition, abnormal processthrombosis, fibrosis
-pathydisease, disorderneuropathy, cardiomyopathy
-peniadeficiency, decreasethrombocytopenia, leukopenia
-plastysurgical repairrhinoplasty, angioplasty
-plegiaparalysishemiplegia, paraplegia
-rrheaflow, dischargediarrhea, rhinorrhea
-scopyvisual examinationcolonoscopy, bronchoscopy
-stomysurgical openingcolostomy, tracheostomy
-tomyincision, cutting intolaparotomy, craniotomy
-uriaurine conditionhematuria, proteinuria
-phagiaeating, swallowingdysphagia, polyphagia

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Frequently Asked Questions

What is a medical terminology suffix?

A suffix is the ending of a medical term that classifies it — typically as a condition (-itis, -osis), procedure (-ectomy, -scopy), specialty (-ology, -iatry), or symptom (-algia, -emia). Suffixes usually determine what kind of word you're reading.

How many medical suffixes do I need to know?

About 80–100 suffixes cover almost all clinical vocabulary. They cluster into a small number of categories (inflammation, removal, viewing, study of, pain, blood condition), which makes them faster to learn than roots.

What's the difference between -ectomy and -otomy?

An -ectomy is the surgical removal of something (appendectomy = remove the appendix). An -otomy is a surgical incision into something (tracheotomy = cut into the trachea, without removing it). One letter, very different procedures.

What does the suffix -itis mean?

-itis means inflammation. It's one of the highest-frequency medical suffixes: arthritis (joint), tonsillitis (tonsils), gastritis (stomach), pericarditis (around the heart), nephritis (kidney).

What are the most common medical terminology suffixes?

-itis (inflammation), -osis (condition), -emia (blood), -algia (pain), -ectomy (removal), -otomy (incision), -ostomy (creating an opening), -scopy (viewing), -graphy (recording), -ology (study of), and -pathy (disease).