Medical Terminology Prefixes (With Meanings and Examples)

A medical prefix sits at the front of a term and usually signals number, size, position, direction, time, or amount. Here are the high-frequency prefixes with meanings and clinical examples.

PrefixMeaningExample
a-, an-without, absence ofapnea, anemia
brady-slowbradycardia
tachy-fast, rapidtachycardia
dys-difficult, abnormal, painfuldyspnea, dysphagia
hyper-excessive, above normalhypertension
hypo-below normal, deficienthypoglycemia
endo-within, innerendocarditis
peri-around, surroundingpericarditis
epi-upon, aboveepidermis
inter-betweenintercostal
intra-withinintravenous
sub-under, belowsubcutaneous
supra-above, oversuprapubic
poly-many, muchpolyuria
olig-, oligo-few, scantyoliguria
anti-againstantibiotic
brady-slowbradypnea
neo-newneonatal
post-after, behindpostpartum
pre-before, in front ofpreoperative
tachy-rapidtachypnea
macro-largemacrocyte
micro-smallmicroscope
leuk-, leuko-whiteleukocyte
erythr-, erythro-rederythrocyte
cyan-, cyano-bluecyanosis

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Frequently Asked Questions

What is a medical terminology prefix?

A prefix is the beginning of a medical term that modifies its meaning, usually indicating location (sub-, supra-), number (bi-, multi-), time (pre-, post-), or quality (hyper-, hypo-). For example, in 'hypertension', 'hyper-' means excessive.

How many medical terminology prefixes do I need to learn?

Around 100 high-frequency prefixes cover roughly 90% of clinical vocabulary. Our prefix decks focus on these, organized by category (location, quantity, color, etc.) for easier recall.

What's the difference between a prefix and a root word?

A prefix attaches to the front and modifies meaning; a root names the body part, system, or condition. In 'pericarditis', 'peri-' (around) is the prefix, 'cardi' (heart) is the root, and '-itis' (inflammation) is the suffix.

Are medical prefixes the same as everyday English prefixes?

Often yes — anti-, pre-, sub-, super-, re-, and trans- carry the same meanings in medical and general English. Greek and Latin prefixes (a-/an-, dys-, eu-) are more specific to medical terminology.

What are the most common medical terminology prefixes?

Hyper- (excessive), hypo- (deficient), tachy- (fast), brady- (slow), poly- (many), oligo- (few), peri- (around), endo- (inside), ecto-/exo- (outside), and dys- (difficult/abnormal) appear in thousands of clinical terms.